Published on:Jan/2016
    Journal of Pharmacy Practice and Community Medicine, 2016; 2(2):35-39
    Review Article | doi:10.5530/jppcm.2016.2.3

    Past, Present and Future about Ebola Virus Diseases: An Updated Review

    Authors and affiliation (s):

    Akash Mali*1, Bodake Swapnil2, Jadhav Pooja3, Mali Dwaraka4, Jurgelevičius Vaclovas5

    1Department of Molecular Biology and Biotechnology, University of Wurzburg, Wurzburg, GERMANY.

    2Department of Nursing, ANM, Government Hospital, ZP, Satara, Maharashtra, INDIA.

    3Department of Pharmacy, HelpageIndia, Organization, Khandala, Maharashtra ,INDIA.

    4Department of Pharmacology, SDVV College of Pharmacy and Research Center Panvel, Mumbai, INDIA.
    5Department of Laboratory Diagnostics, Senior Scientist, Vytautas Magnus University, Lithuania, EUROPE.


    Ebola virus is responsible for the Ebola virus diseases. The epidemic of Ebola hemorrhagic fever is a deadly disease of animal can also be transmitted to human and non-human primates. The virulence of Ebola virus involved in several immune evasion mechanisms that include an inhibition of type I interferon responsible for innate immunity, epitope masking, etc. recently Ebola virus is sexually transmitted which was reported in Liberia has associated with new clusters in regions previously declared Ebola-free. There is no appropriate antiviral vaccine or therapy is not available to work against EBOV infection in humans. However, supportive recovery practices are performed include high-fluid intake, ventilator support and broad-spectrum antibiotic therapy. The treatment and diagnosis is very important because these kind of dangerous viruses are possibly used for bio-weapons. The present review describes briefly about virology, epidemiology, pathophysiology, transmission, diagnosis and treatment of Ebola viral disease.

    Key words: Ebola virus, Filovirus, RT-PCR, Drug, Vaccine Development.



    Cite this article as

    Mali A, Swapnil B, Pooja J, Dwaraka M, Vaclovas J. Past, Present and Future about Ebola Virus Diseases: An Updated Review. Journal of Pharmacy Practice and Community Medicine. 2016;2(2):35-9. Abstract