01533nas a2200181   4500008004100000245007000041210006600111260001800177300001000195490000600205520098200211653002901193653001201222653002801234653001701262100002801279856004401307       2022                        eng d00aA Case Report on Hereditary Spherocytosis in a 22-Year-Old Female0 aCase Report on Hereditary Spherocytosis in a 22YearOld Female  cNovember 2022  a49-500 v83 a<p class="rtejustify">Hereditary spherocytosis is a rare genetically transmitted spherical shaped red blood cell disorder which leads to hemolytic anemia. The symptoms vary from asymptomatic to severe life-threatening anemia. The management includes splenectomy, blood transfusion and vitamin supplements. A 22-year-old female comes to tertiary care hospital with the complaints of fever, yellowish discoloration of eyes and urine. She was diagnosed with hereditary spherocytosis 10 years back and was continuously on blood transfusion. On day 1, her hemoglobin was 6.3 g/dL which falls under life-threatening anemia, total bilirubin was 7.9 g/dL, and direct bilirubin was 0.9 g/dL. She was given with blood transfusion for two days and hemoglobin level raised to 10 g/dL. This case presents life-threatening anemia and icterus associated with severe hereditary spherocytosis. The treatment in hereditary spherocytosis is quite challenging often because of its obscurity.</p>
10aHereditary spherocytosis10aIcterus10aLife-threatening anemia10aTransfusion.1 aPathan, Umme, Habeeba A  uhttp://jppcm.org/article/2022/8/4/49-50