02628nas a2200265 4500008004100000245006100041210006100102260001500163300000800178490000600186520191200192653001902104653003302123653001302156653001102169653001402180100001702194700001902211700001702230700001702247700001702264700002002281700001902301856004202320 2023 eng d00aImpact of Treatment on Asthma Control in Quetta Pakistan0 aImpact of Treatment on Asthma Control in Quetta Pakistan cMarch 2023 a1-50 v93 a

Background: Poorly controlled asthma may lead to decreased lung function, increase the risk of complications and more episodes of exacerbations, increased healthcare utilization, including more frequent hospitalizations and emergency room visits. Regular monitoring of asthma symptoms and lung function can help identify any potential issues in asthma control and ensure optimal management. Objectives: The study aims to assess the asthma control by the usage of asthma controller medications especially, corticosteroids, bronchodilators and leukotriene modifiers, among patients receiving treatment through well-validated questionnaire. Materials and Methods: A cross-sectional study with a sample of 361 was conducted in different public hospitals outpatient departments and clinics of Quetta Pakistan by using a convenience sampling technique. The Asthma Control Questionnaire (ACQ) was used to measure the asthma control of the asthmatic patients. The descriptive and inferential statistics have been done by using SPSS version 20 with a p value <0.05. Results: The study found that an average score of asthma control was 3.1±1.10 thereby indicating uncontrolled asthma with also 62.3% of study participants had uncontrolled asthma, no patient had controlled asthma. An increased number of medications including the use of corticosteroids and leukotriene modifiers posed an impact on asthma control of the study population. Conclusion: The study concluded that corticosteroids and leukotriene modifiers can be effective in asthma control and it is suggested for the future studies that route of administration and treatment guidelines must also be determined along with the asthma control to gain a complete picture of impact of treatment and management on any health outcomes.

10aAsthma Control10aAsthma Control Questionnaire10aPakistan10aQuetta10aTreatment1 aSehar, Sadia1 a-ul-Haq, Noman1 aTahir, Maria1 aRiaz, Sohail1 aNasim, Aqeel1 aSaood, Muhammad1 aYasmin, Riffat uhttp://jppcm.org/article/2023/9/1/1-502673nas a2200277 4500008004100000245010900041210006900150260001600219300001000235490000600245520184600251653001502097653002102112653002902133653003402162653001202196100001602208700001902224700002002243700002002263700001702283700001702300700001702317700001702334856004402351 2022 eng d00aDrug Utilization Pattern in Elderly Hospitalized Patients in Tertiary Care Hospitals of Quetta, Pakistan0 aDrug Utilization Pattern in Elderly Hospitalized Patients in Ter cAugust 2022 a26-330 v83 a

Background: Changes in Pharmacokinetics and pharmacodynamics in different age groups, especially in elderly age group, have extensively been documented and studied and concurrent chronic diseases may underlie polypharmacy in elderly. Aim: The aim of this study was to assess drug utilization pattern in elderly hospitalized patients in tertiary care hospitals of Quetta. Methods: Specifically, designed questionnaire based, cross sectional study was conducted in Bolan Medical Complex Hospital and Sandeman Provincial Hospital Quetta with total of 397 participants. Non-Probability convenience sampling technique was used in this study. Cronbach alpha test was applied to check reliability of questionnaire, Cronbach alpha value was 0.886 that is acceptable range. Results: Majority of the participants were from age group 60 to 70 years (n=301, 75.8%), fever and cough were present in majority of hospitalized patients (n=180,11.7%). Majority (n=232, 58.4%) of participants were having uncontrolled disease with yearly health service utilization of more than 3 times (n=234, 58.9), medication recommended to majority (146, 36.8%) of participants were 4. Ceftriaxone was mostly prescribed in cough (n=162,90%), hypertension (n=114, 67.1%), fever (n=154, 85.6%) of cases, while in gastritis omeprazole was mostly prescribed (n=84, 73.7%). Most of the hospitalized patients were complaint to ceftriaxone, omeprazole, dimenhydrinate and diclofenac sodium. Conclusion: Ceftriaxone was most prescribed drugs among elderly patients that were admitted in different specialty departments. Most of the elderly patients had uncontrolled disease status. This study concluded that the compliance to medication was 82.1% of elderly patients.

10aCompliance10aDrug Utilization10aDrug utilization pattern10aElderly hospitalized patients10aQuetta.1 aAli, Tayyab1 aHaq, Noman, ul1 aRazaque, Ghulam1 aSaood, Muhammad1 aNasim, Aqeel1 aShah, Yasmin1 aTahir, Maria1 aKhan, Ramina uhttp://jppcm.org/article/2022/8/2/26-3301308nas a2200181 4500008004100000245008400041210006900125260001800194300000700212490000600219520078200225653000801007100001701015700001901032700001601051700001801067856004101085 2019 eng d00aGestational Diabetes Mellitus in Pakistan: Undiagnosed Threat to Pregnant Women0 aGestational Diabetes Mellitus in Pakistan Undiagnosed Threat to  cDecember 2019 a800 v53 a

Dear Editor,

Gestational Diabetes Mellitus (GDM) is a rare disorder and due to non-uniformity in its diagnostic criteria and changes over time in the recommended glucose values,[1] it is a major and a severe problem during pregnancy. But the time has reached to draw peoples’ attention towards this major medical complication of pregnancy. Women with risk factors such as age greater than 25 years; being overweight i.e., BMI > 27kg/m2 before pregnancy and BMI > 30kg/m2 during pregnancy; family history of diabetes; the previous history of pregnancy-induced hypertension and weight of the previous baby of ≥4.5kg have a greater incidence of hyperglycemia during their pregnancy period.[2]

10aNil1 aTahir, Maria1 aHaq, Noman, ul1 aAbid, Arooj1 aZafar, Abeera uhttp://jppcm.org/article/2019/5/4/80