01606nas a2200181 4500008004100000245009100041210006900132260001500201300000600216490000600222520106300228653000801291100001601299700001901315700002601334700002401360856004001384 2023 eng d00aVitamin D3 Analogues and Laboratory Tests Interactions: Public Health Awareness Glance0 aVitamin D3 Analogues and Laboratory Tests Interactions Public He cMarch 2023 a60 v93 a

Vitamin-D is available in the market in three different forms; cholecalciferol, alfacalcidol both of them are inactive and converted into active form calcitriol.[1] The conversion of both occurs by passing on liver hepatocytes by (25-hydroxylase) and kidneys (1-alfa-hydroxylase) while alfacalcidol is converted into active form only by the liver.[2,3] Thus, it means that those individuals whose Renal Function Tests (RFTs) and Liver Function Tests (LFTs) are raised they are unable to get benefits from cholecalciferol and those with raised LFTs will not get benefits from alfacalcidol thus the selection of choice in this condition will be calcitriol or 1, 25-dihydroxycholecalciferol is depicted in the (Figure 1).[4-6] To the best of our knowledge this will be the first attempt to highlight the selection of Vitamin D3 from different analogues. The main aim of this short comment to aware the public regarding the use of better alternative for the patients from the rest of three.

10aNil1 aKhan, Majid1 aRiaz, Muhammad1 aAmin, Muhammad, Usman1 aKhan, Ashraf, Ullah uhttp://jppcm.org/article/2023/9/1/600834nas a2200157 4500008004100000245004200041210004200083260001900125300000700144490000600151520041200157653000800569100002900577700002900606856004100635 2022 eng d00aEffect of Exercise on Drug Absorption0 aEffect of Exercise on Drug Absorption cSeptember 2022 a440 v83 a

Dear Editor,

Exercise is the systematic execution of physical activity for a specific purpose. At rest, in humans, skeletal muscle receives between 15% and 20% of the cardiac output, while during maximal exercise, this percentage reaches values of 80% to 90%.[1] Exercise places great demand on circulation. Read More . . .

10aNil1 aAbubakar, Ibrahim, Ahmad1 aAbdulrahman, Jibo, Garba uhttp://jppcm.org/article/2022/8/3/4402031nas a2200169 4500008004100000245004900041210004700090260001600137300001000153490000600163520158200169653000801751100002001759700001701779700002101796856004401817 2021 eng d00aCOVID-19 Pandemic and Bio-Ethical Challenges0 aCOVID19 Pandemic and BioEthical Challenges cAugust 2021 a20-230 v73 a

The Coronavirus disease (COVID-19) wreaked havoc across the globe with the onset of year 2020, which posed an extra ordinary situation in front of humankind. As the pandemic continues to progress, everyday challenges are faced by health worker in the history of mankind, because medical profession is bound by ethics our health workers are facing unprecedented ethical dilemmas and challenges in the era of COVID-19 pandemic.

Beauchamp TL and Childress JF articulated following four tenets of Biomedical ethics with which all the healthcare workers must abide Autonomy, Justice, Nonmaleficence and Beneficence.[1] India reported a record high of 352 991 daily confirmed COVID-19 cases and 2812 deaths on 25 April, according to the Johns Hopkins University database.[2] Hospitals in India have been pleading publicly for help as they run out of oxygen. At least 20 COVID-19 patients died at the private Jaipur Golden Hospital in North West Delhi following a dip in oxygen pressure.[3]

Scarcity of Resources in India in COVID-19 Pandemic forced country to take help from other countries in this pathetic condition. The UK announced it is sending nine airline container loads of supplies to India, including 495 oxygen concentrator devices, 120 non-invasive ventilators, and 20 manual ventilators. The first shipment is to arrive in New Delhi on 27 April with further shipments to follow later in the week.[4] Read more...

10aNil1 aSingh, Abhishek1 aOhlan, Sunny1 aAgrawal, Deepika uhttp://jppcm.org/article/2021/7/2/20-2301722nas a2200157 4500008004100000245009200041210006900133260001600202300001000218490000600228520121900234653000801453100003001461700002901491856004401520 2021 eng d00aRegular Physical Activity and Exercise in Prevention and Management of Diabetes Melitus0 aRegular Physical Activity and Exercise in Prevention and Managem cAugust 2021 a39-400 v73 a

Dear Editor,

Diabetes Mellitus (DM) is a group of metabolic diseases characterized by chronic hyperglycemia resulting from defects in insulin secretion, insulin action, or both.[1] The national Diabetes Data Group (2000) indicated that DM consists of three different types, which include: Type 1, Type 2 and gestational diabetes.[2]

Type I DM also used to be referred to as juvenile diabetes or insulindependent diabetes and it is due to the destruction of β cells of the pancreas.[3] Also, Type 2 DM was previously referred to as “adult-onset diabetes”. It is used to be called non-insulin dependent diabetes or adult-onset diabetes.[4] Here, the pancreas usually produces some insulin, but the insulin might not be enough or the body cells get resistant to it. As such, the body cannot utilize the insulin that is released.[5] However, the third type of diabetes mellitus is the gestational diabetes, and it occurs when pregnant women without a previous history of diabetes develop high blood sugar levels.[6]Read more...

10aNil1 aTunde, Gbonjubola, Yusuff1 aAbubakar, Ibrahim, Ahmad uhttp://jppcm.org/article/2021/7/2/39-4002193nas a2200181 4500008004100000245004900041210004700090260001500137300000600152490000600158520173000164653000801894100001501902700001901917700001901936700001601955856004001971 2020 eng d00aBeef Ban in India: A Multi-dimensional Issue0 aBeef Ban in India A Multidimensional Issue cApril 2020 a10 v63 a

The Economic Times published an article in January 2019, highlighting the increasing problem of stray cattle in rural India. Four years ago, several states in India began making the decree to protect cows from slaughter at the end of their productive lives.[1] The largely Hindu population in India considers cows sacred and does not condone their slaughter.

In 2012, there were only 5 million stray cattle roaming the Indian streets, but now there is an estimated 40 million unproductive cattle at risk of being abandoned.[1] India only has 5,000 shelters, each with a capacity of 200; but these are near enough.[1] Cattle are being abandoned because they are beyond the age of productivity and the cost for a farmer to keep an unproductive cow is Rs. 7500/month. Prior to the beef ban, farmers could sell dried up cows for Rs. 20,000 to Rs. 50,000 each depending on their age. Farmers are facing a severe economic deficit since they can no longer sell their cattle for profit.[1] The abundance of stray cattle has also led to Indians being physically attacked. Cows trespassing on farmland and destroying crops have recently led to them being locked up inside schools and hospitals for containment.[1] Currently, there is much controversy between Indian political parties on resolving the economic and social stress that cow abandonment has caused on several states in India.[2] There has been argument about the former cattle trade being important for the rural economy and necessary to provide revenue for dairy farmers' unproductive cattle.[2]  Read more. . .

10aNil1 aKhan, Anam1 aRiedel, Taylor1 aHussain, Rabia1 aPatel, Isha uhttp://jppcm.org/article/2020/6/1/101673nas a2200169 4500008004100000245004900041210004700090260001400137300001000151490000600161520123300167653000801400100001801408700001701426700001601443856004401459 2020 eng d00aFecal-Oral Transmission of COVID-19 in India0 aFecalOral Transmission of COVID19 in India cJune 2020 a18-190 v63 a

Although the spread of COVID-19 through droplets, surface contact and aerosolized transmission has been well-publicized, the fecal-oral route is yet another identified method of transmission. According to a meta-analysis by the New England Journal of Medicine, it was found that fecal viral shedding continues throughout the disease, even after nasopharyngeal tests appear negative. Moreover, gastrointestinal symptoms seem to be common for COVID-19 patients, with a prevalence of approximately 18%.[1,2] It was also found that patients with digestive symptoms experience significantly longer hospital stays.[3] As India’s number of COVID-19 cases continues to increase, concerns about fecal-oral transmission are being raised in a country that has the highest open defecation rates in the world, where approximately 620 million people defecate in the open. It is a problem that comes with severe public health consequences, including diarrhea, high child mortality, spread of diseases, malnutrition and stunting of growth.[4] Public health officials should be concerned about how this will affect India’s transmission of COVID-19. Read more.....

10aNil1 aGoff, Allyson1 aAhmad, Akram1 aPatel, Isha uhttp://jppcm.org/article/2020/6/2/18-1902452nas a2200145 4500008004100000245008900041210006900130260001700199300001000216490000600226520200600232653000802238100001602246856004402262 2020 eng d00aRole of Clinical Pharmacist in Context of World Health Organization against COVID-190 aRole of Clinical Pharmacist in Context of World Health Organizat cOctober 2020 a44-450 v63 a

Dear Editor,

Since December 2019, the outbreak of novel human virus on the name of COVID-19 spread in China from Wuhan city around the world to 183 countries in 2020.[1] This virus considered lethal for many people. Most of the people who infected get respiratory symptoms include cough, shortness of breath, sneezing and fever. The novel virus transmitted in contact person to person via droplets of cough or sneezes from infected person or animal. High risks to those peoples who are in outbreak areas or with other complications include immune-compromised patients, diabetes mellitus, cardiac diseases and any other co-morbidities.[2] Clinical Pharmacists are more easily accessible healthcare professionals to public and key figures of health care team regarding infectious diseases. According to Amir M et al. Clinical Pharmacy is the liaison of pharmacist with physician in which Clinical pharmacists prescribing medications.[3,4] Wasim et al. articulated that Clinical Pharmacists are independent prescribers in United Kingdom.[5] In current pandemic pharmacists may consider secondary prescriber due to physician’s self-illness and inpatient focuse.[1] World Health Organization being a standard organization around the world providing health to worldwide population, mandate some qualities upon the Pharmacists that a good pharmacist bears seven qualities every quality called as star thus named as “Seven stars Pharmacist” includes communicator, teacher, decision maker, leader, manager, lifelong learner, caregiver[6] additional two are researcher and pharmapreneur thus total becomes “Nine stars Pharmacist” (Figure 1), almost all of these are implemented in developed countries in outbreak of novel corona virus which was expected WHO few years ago now the time for these professionals proving their selves. Read more...

10aNil1 aKhan, Majid uhttp://jppcm.org/article/2020/6/3/44-4501429nas a2200181 4500008004100000245006200041210006000103260001400163300001000177490000600187520093600193653000801129100001501137700001801152700001701170700001601187856004401203 2020 eng d00aTo Suppress or to Mitigate COVID-19: That is the Question0 aTo Suppress or to Mitigate COVID19 That is the Question cJune 2020 a20-210 v63 a

In India, public health experts have been debating the most effective way of combating COVID-19 (or SARS-COV-2 virus) while balancing the amount of lives lost and trying to preserve the economy. This virus is particularly challenging for India as the population is so large, and the healthcare system is still developing to meet the needs of its citizens. While social distancing has been and is being widely practiced worldwide to mitigate the further spread of COVID-19, it is apparent that more aggressive public health measures are needed to further decrease the numbers of infected people. Already, India has extended its lockdown from March 24th to the end of May.[1] By better understanding how this virus propagates, as well as by considering the unique needs of India, experts can better determine the best measures to fight further spread. Read more.....

10aNil1 aKhan, Anam1 aGoff, Allyson1 aAhmad, Akram1 aPatel, Isha uhttp://jppcm.org/article/2020/6/2/20-2101651nas a2200145 4500008004100000245007100041210006900112260001800181300001000199490000600209520122000215653000801435100001801443856004401461 2019 eng d00aBlessing of Knowledge-Based Empathy to Engender Prudent Prescriber0 aBlessing of KnowledgeBased Empathy to Engender Prudent Prescribe cDecember 2019 a58-590 v53 a

“It is the patient who carries the burden of illness, but the compassionate physician shares that burden, lifting it when possible and lightening it when that is all that can be done. This sharing of the burden has always been the hallmark of the medical profession”.[1]

The American University of Antigua, College of Medicine’s Admissions Committee and a few others fells that compassion, strong work ethic, professionalism, knowledge, confidence, humility, passion, empathy, being humane, respectfulness and thoroughness are indispensable prerequisites for a good physician to master.[2,3] Physicians require to own comprehensive and up to date medical knowledge that can be revoked at the drop of a hat.2 Updating medical doctors’ knowledge regularly is an essential necessity, as medical science is changing and progressing, especially the field of pharmacological intervention.[2,4-6] Hereafter, could argue against their acquired knowledge through undergraduate studies.[2] Henceforward, acquisitions and updating knowledge is a fundamental prerequisite to a good physician.[7-9]

10aNil1 aHaque, Mainul uhttp://jppcm.org/article/2019/5/4/58-5901308nas a2200181 4500008004100000245008400041210006900125260001800194300000700212490000600219520078200225653000801007100001701015700001901032700001601051700001801067856004101085 2019 eng d00aGestational Diabetes Mellitus in Pakistan: Undiagnosed Threat to Pregnant Women0 aGestational Diabetes Mellitus in Pakistan Undiagnosed Threat to  cDecember 2019 a800 v53 a

Dear Editor,

Gestational Diabetes Mellitus (GDM) is a rare disorder and due to non-uniformity in its diagnostic criteria and changes over time in the recommended glucose values,[1] it is a major and a severe problem during pregnancy. But the time has reached to draw peoples’ attention towards this major medical complication of pregnancy. Women with risk factors such as age greater than 25 years; being overweight i.e., BMI > 27kg/m2 before pregnancy and BMI > 30kg/m2 during pregnancy; family history of diabetes; the previous history of pregnancy-induced hypertension and weight of the previous baby of ≥4.5kg have a greater incidence of hyperglycemia during their pregnancy period.[2]

10aNil1 aTahir, Maria1 aHaq, Noman, ul1 aAbid, Arooj1 aZafar, Abeera uhttp://jppcm.org/article/2019/5/4/80