TY - JOUR T1 - BCG Induced Lymphadenitis: A Prerequisite in Parental Counseling during Pre and Post Vaccination Program JF - Journal of Pharmacy Practice and Community Medicine Y1 - 2021 A1 - Abhishek Sharma A1 - Gulnaz Bano A1 - Abdul Malik KW - AEFI KW - BCG vaccination KW - FNAC. KW - Lymphadenitis KW - Patient counseling KW - tuberculosis AB -

Bacillus-Calmette-Guerin (BCG) is a live attenuated vaccine and used to prevent tuberculosis since 1921. BCG vaccination is performed as a part of expanded program of immunization (EPI). BCG vaccine is considered as a safe technique of tuberculosis prevention because there are only local adverse reactions seen with this and serious adverse reactions are rare. Lymphadenitis is the most frequent side effect of BCG vaccination. Intradermal BCG vaccination gives rise to erythromatous formation that consists of a cutaneous nodule at the site of injection and subclinical involvement of the regional lymph nodes, which is self limiting and requires no treatment. Lymphadenitis is the most frequent side effect of BCG vaccination. Fine needle aspiration is the quick, safe, and cost effective technique for diagnosis in addition to the management of BCG lymphadenitis. Here we report a case of 10- months’ healthy male patient with left axillary lymphadenitis post BCG vaccination.

VL - 7 IS - 3 ER - TY - JOUR T1 - Unapproved Combination Therapy of Doxycycline and Ivermectin in Covid-19 Pandemic, an Opportunistic Chance of Self-medication: A Case Report JF - Journal of Pharmacy Practice and Community Medicine Y1 - 2020 A1 - Gulnaz Bano A1 - Abhishek Sharma KW - ADE KW - ADRs KW - COVID-19 KW - Doxycycline KW - ICMR KW - Ivermectin KW - Rashes KW - Self-medication AB -

To date, no standard drug therapy has proven effective to counter COVID-19 disease. There are only hit and trial based on assumptions and weak evidence that are directing prescribing practices for asymptomatic to symptomatic and serious cases of COVID-19. ICMR being the apex body, responsible for framing the guidelines for the management of disease in India has not yet approved the use of combination doxycycline and ivermectin in the prophylaxis or treatment of Covid-19 cases but being used in the treatment of COVID-19 infection. Their adverse drug reactions individually are well known among scientific community. Doxycycline ADRs range from gastrointestinal, urogenital, neuropsychiatric, respiratory, nervous system to skin and appendages. We have reported a case of doxycycline induced drug allergy (rashes) all over the trunk and legs as a result of self-medication. The event happened after a female patient had complaints of persistent fever and weakness consumed doxycycline and ivermectin on her friend’s advice and developed rashes on her trunk and legs. The above ADE is very mild but alarming for the medical fraternity that warrants strict compliance with the electronic/text/online prescription. The usage of doxycycline and ivermectin in the treatment of COVID-19 disease, as an indication of treatment should not be considered prior to any concrete evidence or issuance of treatment, guidelines by the apex body in India.

VL - 6 IS - 4 ER -